Adjuvant radiation of patients with involvement of mediastinal lymph nodes (pN2) and complete resection of Non Small Cell Lung Cancer: a retrospective analysis of patients of the department of Radiation Oncology Freiburg

• Conditions: C34; Malignant neoplasm of bronchus and lung

• Registration Number: DRKS00008887
• Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-08-15
• Study Start: 2015-09-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 61

Inclusion Criteria

age >= 18 years,
- pN2 after surgery of the primary tumor and systematic mediastinal lymphadenectomy
- with histologically confirmed NSCLC

Exclusion Criteria

- R1-status after surgery, because then radiation is indicated in any case
- distant metastases
- pN1 or pN3

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival (retrospective evaluation)

Secondary Outcome Measures

Name	Time	Method
1) Loco-regional relapse-free survival: prognostic relevance of the radiation therapy, time interval until progress/relapse after end of radiation therapy or surgery<br>2) Survival without distant metastases<br>3) Therapy-associated toxicity. Acute and long-term implications of the radiation therapy (like radioodermatitis, dysphagia, hemotoxicity, radiopneumonitis/-fibrosis)<br>(retrospective evaluation)<br>