NCT00821665已完成不适用
Blood Glucose Homeostasis in Type 2 Diabetes: the Effects of Saccharose
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 2
- 主要终点
- Hyperglycemia
研究概览
简要总结
Hyperglycemia forms a direct and independent risk factor for the development of cardiovascular co-morbidities in type 2 diabetes. Consumption of sucrose-sweetened soft drinks might further increase the prevalence of hyperglycemic episodes.
The objective of the study was to assess glycemic control in type 2 diabetes patients and healthy lean and obese controls under strict dietary standardization but otherwise free living conditions, with and without the consumption of soft drinks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Lean NGT Group
- •Normoglycemic (according to 2006 ADA guidelines)
- •BMI < 27 kg/m2
- •Obese NGT Group
- •Normoglycemic
- •BMI 30- 35 kg/m2
- •Obese type 2 diabetes Group
- •BMI 30- 35 kg/m2
- •Oral blood glucose lowering medication
排除标准
- •Exogenous insulin use
- •Cardiac disease (any cardiac event in the last 5 years)
- •HbA1c >10%
- •Microalbuminuria: albumin:creatinine ratio >2,5
结局指标
主要结局
Hyperglycemia
时间窗: 24h
次要结局
- Hyperglycemia(Postprandially)
研究者
研究点 (2)
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