Blood Glucose Homeostasis in Type 2 Diabetes: the Effects of Saccharose
Not Applicable
Completed
- Conditions
- Type 2 DiabetesGlycemic Control
- Interventions
- Dietary Supplement: Sucrose consumptionDietary Supplement: water consumption
- Registration Number
- NCT00821665
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
Hyperglycemia forms a direct and independent risk factor for the development of cardiovascular co-morbidities in type 2 diabetes. Consumption of sucrose-sweetened soft drinks might further increase the prevalence of hyperglycemic episodes.
The objective of the study was to assess glycemic control in type 2 diabetes patients and healthy lean and obese controls under strict dietary standardization but otherwise free living conditions, with and without the consumption of soft drinks.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 39
Inclusion Criteria
Lean NGT Group
- Normoglycemic (according to 2006 ADA guidelines)
- BMI < 27 kg/m2
Obese NGT Group
- Normoglycemic
- BMI 30- 35 kg/m2
Obese type 2 diabetes Group
- BMI 30- 35 kg/m2
- Oral blood glucose lowering medication
Exclusion Criteria
- Exogenous insulin use
- Cardiac disease (any cardiac event in the last 5 years)
- HbA1c >10%
- Microalbuminuria: albumin:creatinine ratio >2,5
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Sucrose Sucrose consumption Sucrose Water water consumption Water
- Primary Outcome Measures
Name Time Method Hyperglycemia 24h
- Secondary Outcome Measures
Name Time Method Hyperglycemia Postprandially
Trial Locations
- Locations (1)
Maastricht University
🇳🇱Maastricht, Limbrug, Netherlands