Effects of Acupuncture at ST36 and PC6 on Blood Pressure and Endothelial Dysfunction in Hypertensive Patients

Phase 3

• Conditions: Hypertension
• Interventions: Procedure: acupuncture

• Registration Number: NCT01002846
• Lead Sponsor: Kyunghee University Medical Center

Brief Summary

This is randomised, controlled study about effects of acupuncture on blood pressure and endothelial dysfunction in stage I hypertension patient without medication. Subject will receive 8 weeks of either acupuncture or sham acupuncture, measuring FMD and blood test before and after treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Status Verified: 2009-10
• Study First Submitted: 2009-10-26
• Study First Submitted QC: 2009-10-26
• Last Update Submitted: 2009-10-26
• Study First Posted: 2009-10-27
• Last Update Posted: 2009-10-27
• Primary Completion: 2010-06
• Study Completion: 2010-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Patients age 18-70 diagnosed stage I hypertension ( JNC-7) without taking hypertensive medication

Exclusion Criteria

• Secondary hypertension
• DM
• History of cardiovascular disease
• Taking hypertensive medication
• Taking hyperlipidemic medication
• Smoking
• Pregnancy or feeding woman
• Cannot follow indication or there is no agreement of patient and conservator
• Investigator decide Inappropriate to trial

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
traditional acupuncture	acupuncture	Procedure : ST 36 and PC 6 are selected, subject will undergo 20minute sessions twice a week for 8weeks. Disposable acupuncture needle(4cm sterilized stainless steel) will be inserted up to 1 cm depth
sham acupuncture	acupuncture	Procedure : Beside 1cm of ST 36 and PC 6 are selected( not meridian point), subject will undergo 20 minute. Disposable acupuncture needle(4cm sterilized stainless steel) will be inserted under 1 cm slightly.

Primary Outcome Measures

Name	Time	Method
To assess effects of acupuncture on endothelial function with FMD variation after 8 weeks treatments.	8 weeks

Secondary Outcome Measures

Name	Time	Method
To examine the effects of acupuncture on blood pressure, lipid , hsCRP level variation with ABPM after 8 weeks treatments.	8 weeks

Trial Locations

Locations (1)

Oriental Medicine of Stroke and Nerologic center; 🇰🇷 Seoul, South Korea, Korea, Republic of