Compare Effects of the Mirror Therapy and Robotic Mirror Therapy in Electroencephalography of Healthy Adults and Stroke Patients.

Not Applicable

Completed

• Conditions: Healthy Adults; Stroke Patients
• Interventions: Device: robotic hand

• Registration Number: NCT04236089
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Mirror therapy has recently attracted increasing attention; however, most patients have the difficulties to perform mirror therapy due to limited imaginary ability. A mirror robotic hand system was developed, which consisted with a wearable exoskeletal hand, sensor glove, and a control box. The patient's unaffected hand wears the sensor glove, the affected hand wears the wearable exoskeleton hand, and the unaffected hand does the certain transitive and intransitive tasks as the mirror group, and then makes the affected hand do the same movements driven by the exoskeleton robotic hand. The investigators hypothesize that combining both approaches might facilitate the sensorimotor cortex that controls movement and might augment somatosensory input and further treatment efficacy. This study is aimed at investigating the effects of Mirror therapy and robotic mirror therapy on motor cortical activations in healthy adults and stroke patients using electroencephalography. All participants will perform the conditions of resting, moving right hand with or without robotic hand as the baseline data, then they will do mirror therapy using the right hand as active hand, or wearing robotic hand doing mirror therapy in random sequence. Electroencephalography (EEG) assessment will be done to assess the neurophysiologic effects of the different interventions. The investigators will use a questionnaire to assess the subjective opinion about the different interventions.

combined with execution (video AOE). The investigators will use the pair-t test to assess the within subjects differences in EEG and the questionnaire results.

This study will be done during 2020/02/01 - 2021/03/31.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-01
• Study First Submitted: 2020-01-17
• Study First Submitted QC: 2020-01-20
• Study First Posted: 2020-01-22
• Study Start: 2020-02-01
• Primary Completion: 2020-11-30
• Study Completion: 2020-12-31
• Last Update Submitted: 2021-03-03
• Last Update Posted: 2021-03-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• healthy adults: right handed, with normal upper extremity and cognition functions
• stroke patients:one side upper limb spasticity

Exclusion Criteria

• 1. wrist weakness or deformity 2. skin problem 3. musculoskeletal injury of upper extremities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
robotic mirror therapy of stroke patients	robotic hand	Robotic mirror therapy in electroencephalography of stroke patients.
robotic mirror therapy of healthy adults	robotic hand	Robotic mirror therapy in electroencephalography of healthy adults.

Primary Outcome Measures

Name	Time	Method
Electroencephalography assessment	1.5hours	Compare the brainwave of the different interventions through Fourier Transform

Secondary Outcome Measures

Name	Time	Method
Questionnaire	30 minutes	Collect the subjective opinion about the different interventions

Trial Locations

Locations (1)

Department of Rehabilitation, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung, Taiwan; 🇨🇳 Kaohsiung, Taiwan