NCT03678584已完成不适用
Chaetoglobosin A Supplementation to ICSI Handling Medium
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 5
- 主要终点
- Oocyte Survival after ICSI
研究概览
简要总结
Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc. Chaetoglobosin A serves to facilitate spindle or pronuclear transfer procedures helping to reduce the damage rate with no harm reported. Using Chaetoglobosin A during ICSI could serve to rescue some oocytes from the degeneration allowing for more chances of viable zygotes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 42 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All ICSI participants agreed
排除标准
- 未提供
研究组 & 干预措施
Handling Medium Supplemented with Chaetoglobosin A
Experimental
干预措施: Medium Supplemented with Chaetoglobosin A (Other)
handling Medium as it is.
No Intervention
结局指标
主要结局
Oocyte Survival after ICSI
时间窗: two days
Survived oocytes per MII injected
次要结局
- Rate of top-quality embryo(6 days of culture)
- blastocyst formation and quality(6 days of culture)
- Fertilization rate(6 days of culture)
- Ongoing pregnancy rate(12 weeks)
- blastocyst utilization rate(6 days of culture)
- clinical pregnancy rate(7 weeks)
- Implantation rate(7 weeks)
研究者
Muhammad Fawzy
IVF Lab Director
Ibn Sina Hospital
研究点 (5)
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