Is Perfusion Index an Indicator of Block Success in Ultrasound-guided Infraclavicular Brachial Plexus Block

Not Applicable

Completed

• Conditions: Perfusion Index; Carpal Tunnel Syndrome
• Interventions: Procedure: Infraclavicular nerve block; Procedure: Without nerve block

• Registration Number: NCT04921891
• Lead Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Brief Summary

The infraclavicular nerve block, which is frequently preferred in upper extremity surgeries, provides additional advantages such as reduction in opioid consumption by providing analgesic effect in the postoperative period as welll. The success of peripheral nerve blocks is usually assessed by subjective feedback from the patient, and patient cooperation is needed. The aim of this study is to assess whether the perfusion index level, which can be measured noninvasively, can be a predictor of the infraclavicular block success.

Detailed Description

Thirty patients who were operated on for carpal tunnel syndrome under infraclavicular brachial plexus block were included in our study. After the procedure, at 10-minute intervals, the sensory block was assessed by a pinprick test, and the motor block was assessed by the ability to flex the hand and the forearm. In addition, PI and skin temperature were measured 0-10-20-30 minutes after the block and at postoperative 2, 4, and 6 hours. 30 minutes after the measurements, the surgical procedure was allowed to begin in patients with successful block.

Study Timeline

• Study Start: 2014-04-15
• Primary Completion: 2014-04-15
• Study Completion: 2014-10-30
• Status Verified: 2021-06
• Study First Submitted: 2021-06-01
• Study First Submitted QC: 2021-06-04
• Last Update Submitted: 2021-06-04
• Study First Posted: 2021-06-10
• Last Update Posted: 2021-06-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Ages of 18-75
• Patients who will diagnose with carpal tunnel syndrome by electroneuromyography (ENMG), and will undergo unilateral surgery under elective conditions
• ASA I-II-III patients

Exclusion Criteria

• Patients who will refuse this method
• Neurological deficits,
• Diabetes mellitus,
• Local anesthetic allergy,
• Morbidly obese,
• Peripheral vascular disease, coronary artery disease, or coagulopathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Blocked arm	Infraclavicular nerve block	The investigators performed an infraclavicular nerve block to the operated arm group to provide anesthesia.
Unblocked arm	Without nerve block	The upper extremity without block was assigned as the control group, and a comparison was made between the two upper extremities.

Primary Outcome Measures

Name	Time	Method
Evaluation of whether perfusion index is a reliable and objective method to indicate block success	6 hours postprocedurly	Perfusion index was measured up to 6 hours after the procedure.

Secondary Outcome Measures

Name	Time	Method
Determining of a cut-off value for PI and PI ratio for a successful block.	Up to 6 hours after the procedure	There may be changes in the cut-off value depending on the applied plexus area, local anesthesia, volume and concentration of LA and the applied assistive technique (ultrasound or nerve stimulator). For both this reason and due to the high variability in the PI values, the PI ratio was calculated to predict block success.

Trial Locations

Locations (1)

Bakirkoy Dr. Sadi Konuk Research and Training Hospital; 🇹🇷 Istanbul, Bakirkoy, Turkey