Infraclavicular Perineural Dexmedetomidine

Not Applicable

Completed

• Conditions: The Analgesic Effects
• Interventions: Drug: Bupivacaine; Drug: Dexmedetomidine

• Registration Number: NCT02550782
• Lead Sponsor: Cukurova University

Brief Summary

Infraclavicular block is one of the peripheral nerve block used in upper extremity surgery. Adjuvant agents are used in peripheral nerve blocks to increase the duration and block quality. We investigated that the effects of patient-controlled perineural dexmedetomidine application on postoperative analgesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09
• Study First Submitted: 2015-09-14
• Study First Submitted QC: 2015-09-14
• Study First Posted: 2015-09-16
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2017-02
• Last Update Submitted: 2017-02-26
• Last Update Posted: 2017-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• be undergoing distal upper extremity surgery
• Be between 18-65 years
• to agree to participate in research

Exclusion Criteria

• allergy to dexmedetomidine
• AV block or bradycardia
• being serious cardiac - liver - kidney function disorders
• Being coagulopathy
• neuropathy in the upper extremity
• adrenoceptor agonists or antagonists use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
perineural bupivacaine	Bupivacaine	patient-controlled infraclavicular perineural bupivacaine (1% bupivacaine (marcaine), 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
perineural bupivacaine	Dexmedetomidine	patient-controlled infraclavicular perineural bupivacaine (1% bupivacaine (marcaine), 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
perineural dexmedetomidine	Dexmedetomidine	patient-controlled infraclavicular perineural dexmedetomidine (1% bupivacaine + 200 mic / 100cc dexmedetomidine, 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
perineural dexmedetomidine	Bupivacaine	patient-controlled infraclavicular perineural dexmedetomidine (1% bupivacaine + 200 mic / 100cc dexmedetomidine, 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)

Primary Outcome Measures

Name	Time	Method
visual analog scale	3 month	Scores range from 0 \[no pain\] to 10 \[worst possible pain

Secondary Outcome Measures

Name	Time	Method
The effect of dexmedetomidine to the Ramsey Sedation Scale	3 month
side effects	3 month

Trial Locations

Locations (1)

Erzincan Üniversity; 🇹🇷 Erzincan, Merkez, Turkey