Main Features and Ventilatory Management of Patients With ARDS Caused by COVID-19
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Hospital Clinic of Barcelona
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Discontinuation from mechanical ventilation
Study Overview
Brief Summary
Patients with the acute respiratory distress syndrome (ARDS) have markedly varied clinical presentations. Main characteristics of mechanically ventilated ARDS caused by COVID-19, and adherence to lung-protective ventilation strategies are not well known.
Detailed Description
This is a multicenter, prospective, observational study in consecutive, mechanically ventilated patients with ARDS caused by COVID-19 (as defined by the Berlin criteria and confirmed COVID-19 infection in a respiratory tract sample), admitted into a network of 27 Spanish and Andorran intensive care units (ICUs). Clinical features, ventilatory management, and clinical outcomes will be examined
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •aged 18 years or older
- •intubated and mechanically ventilated
- •confirmed COVID-19 infection in a respiratory tract sample
- •acute onset of ARDS, as defined by the Berlin criteria
Exclusion Criteria
- •patients with non-confirmed SARS-CoV-2 infection according to WHO guidance
- •patients with no information on respiratory parameters
- •non- intubated patients
Outcomes
Primary Outcomes
Discontinuation from mechanical ventilation
Time Frame: 28 days
Secondary Outcomes
No secondary outcomes reported
Investigators
Carlos Ferrando Ortolá
Head of Surgical Intensive Care Unit
Hospital Clinic of Barcelona