Efficacy of polyherbal combination Guggulu, Guduchi, Manjistha in the management of Vatarakta (hyperuricemia)

Phase 2

• Conditions: Health Condition 1: E790- Hyperuricemia without signs of inflammatory arthritis and tophaceous disease

• Registration Number: CTRI/2024/08/072046
• Lead Sponsor: Government of West Bengal

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Patient having classical signs and symptoms of Vatarakta mentioned in Ayurvedic text like Ruk(pain), Toda (pricking pain), Sparsha asahatva(tenderness), Shopha (swelling), Raga(redness), Daha (burning sensation) and Stabdhata(stiffness) of sandhis of pada and hasta

2.Serum uric acid level

IN Female- more than 6mg/dl but less or equal 9mg/dl

IN Male -more than 7mg/dl but less or equal 10mg/dl

3.Patients who agreed to follow the study protocol and give constant for clinical trial.

Exclusion Criteria

1.Patients suffering from diabetes mellitus and uncontrolled hypertension,malignant disorders, genetic disorders, renal disorders.

2.Any other inflammatory joint disorders like rheumatoid arthritis, tubercular arthritis, septic arthritis, psoriatic arthritis

3.Patients having deposition of monosodium urate monohydrate crystals in joints or having tophi.

4.Pregnant woman and lactating mother suffering from arthritis.

5.Severe deformity and ankylosing of the joints.

6.Patients who are not willing to come under trial or give consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
serum uric acid level in female less than 6 mg/dl in male less than 7mg/dlTimepoint: 60 days

Secondary Outcome Measures

Name	Time	Method
TO PREVENT URATE CRYSTAL (TOPHI) FORMATIONTimepoint: 60 DAYS