Changes in Muscle Morphology Resulting From Anterior Cruciate Ligament Reconstruction
- Conditions
- Isolated Anterior Cruciate Ligament Rupture
- Registration Number
- NCT01537588
- Lead Sponsor
- Panam Clinic
- Brief Summary
The aim of this study is to gain new knowledge on the impact of hamstring tendon harvest and apply that knowledge to the treatment and management of patients who undergo anterior cruciate ligament (ACL) reconstruction. There are three main components of this study:
1. How do muscle shape, size, strength, and ability to function change following hamstring grafting for ACL reconstruction;
2. How does physical activity change following ACL reconstruction;
3. Is there a difference in outcome if graft harvest is done from the injured versus uninjured limbs
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- between 18 and 50 years old; isolated ACL rupture confirmed on MRI
- other physical or mental health issues that affect ability to complete rehabilitation and/or study follow-ups
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Muscle cross sectional area 12 months post-surgery Measured on bilateral MRI taken from ischial tuberosity to 10 cm below knee joint line
- Secondary Outcome Measures
Name Time Method Physical activity 12 months post-surgery 7-day record of activity using accelerometer.
Knee flexion and extension isokinetic strength 12-months post-surgery Eccentric anc concentric strength measured at 60, 150, and 270 degrees/second on dynamometer in sitting and in 5 degrees hip flexion
Trial Locations
- Locations (1)
Pan Am Clinic
🇨🇦Winnipeg, Manitoba, Canada
Pan Am Clinic🇨🇦Winnipeg, Manitoba, Canada