跳至主要内容
临床试验/NCT03244748
NCT03244748Unknown不适用

Effect of Amiodarone After Ischemic Ventricular Tachycardia Ablation

Yuksek Ihtisas Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2016年1月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
100
试验地点
1
主要终点
Major adverse cardiovascular events

研究概览

简要总结

Ventricular Tachycardia ablation in ischemic cardiomyopathy patients is required procedure in cases when anti-arrhythmic drugs failed. The concern is if adjunctive continuation amiodarone after ablation is needed.

详细描述

Ischemic cardiomyopathy patients have implantable cardioverter defibrillators (ICD) to prevent arrhythmic deaths. Ventricular tachycardia (VT) events with frequent ICD interventions in ischemic cardiomyopathy patients is encountered frequently. Frequents ICD interventions is associated with worse outcomes. Anti-arrhythmic drugs ,mostly amiodarone, are given prevent ventricular arrhythmias and ICD interventions that may not be curative. Ablation of ventricular tachycardia is the suggested treatment when anti-drugs are without effect. After ablation of ventricular arrhythmia the continuation of amiodarone is not well elucidated.

In this study we aimed to enroll ischemic cardiomyopathy patients having frequent ICD interventions despite medical treatment. VT ablation is performed and patients divided into two groups; group one continues having amiodarone after ablation, group two does not have amiodarone after ablation. Both groups will be compared in terms of recurrence and death.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ischemic cardiomyopathy patients applied with frequent ICD interventionor electrical storms and having ejection fraction below 50%. Frequent ICD defined as more than 1 ICD intervention within month. Electrical storm defined as more than 2 ICD intervention within one day.

排除标准

  • Patients with cardiomyopathies other than ischemic etiology

结局指标

主要结局

Major adverse cardiovascular events

时间窗: six months

Death, ICD intervetion

次要结局

未报告次要终点

研究者

发起方
Yuksek Ihtisas Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Fırat Özcan

Associate Professor

Yuksek Ihtisas Hospital

研究点 (1)

Loading locations...

相似试验

Amiodarone Usage After Ischemic Ventricular... | 临床试验