A clinical trial of the effect of remimazolam on postoperative ECG in gynecologic laparotomy

Not Applicable

Recruiting

• Conditions: Patients scheduled for gynecologic laparotomy

• Registration Number: JPRN-jRCT1051220068
• Lead Sponsor: Hori Kotaro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-07-26
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

1) Patients scheduled for genecologic laparatomy
under general anesthesia
2) Patients aged 20 or older
3) Patients classified as ASA-PS 1 or 2 (American Society of Anesthesiologists-Physical Status)
4) Patients who fully understand the study after sufficient explanations and provide the written volun
tary consent

Exclusion Criteria

1) Patients who have contraindication or allergy to sevoflurane or remimazolam
2) Patients who have abnormal QT interval in preoperative ECG
3) Patients who do not have sinus rhythm in preoperative ECG
4) Patients who take antipsychotics, antiarrhythmics, or beta-blockers
5) Patients who have hypokalemia (< 3.5 mEq/L) or hyperkalemia (> 5.5 mEq/L) in preoperative labor
atory data
6) Patients whose BMI are 35 or greater
7) Patient who are considered ineligible for enrolling the study by a principal- or co-investigator

Study & Design

• Study Type: Interventional
• Study Design: Not specified