Influence on estimated glomerular filtration rate in patients with ischemic heart disease and hyperuricemia medicated by febuxostat.

Not Applicable

Recruiting

• Conditions: Ischemic heart disease patients with hyperuricemia

• Registration Number: JPRN-UMIN000009160
• Lead Sponsor: Osaka City University Department of Cardiovascular Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-10-22
• Study Completion: 2015-06-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients with severe renal injury (eGFR<30ml/min) 2)Patients with severe liver injury 3)Patients with severe heart failure (NYHA Class4) 4)Patients with acute myocardial infarction within three months 5)Ineligible patients for any other reasons

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes of estimated glomerular filtration rate(eGFR) between two groups( control group and medicated group).

Secondary Outcome Measures

Name	Time	Method
1)Changes of eGFR between each two groups(control group and medicated group). 2)Changes of uric acid levels, ratio of achiving less than 6.0mg/dl of uric acid levels, changes of microalbuminuria/creatinine, changes of creatinene clearance, changes of C cystatin levels 3)Death, cardiovascular events(acute myocardial infarction, target vessel revascularization, new onset angina pectoris, congestive heart failure, cerebral infarction)