Estimating glomerular filtration rate using measured muscle mass
- Conditions
- Chronic renal failure classified as stage 1-4 (mild impairment to pre-end stage renal disease, Levey et al., 2003)
- Registration Number
- EUCTR2004-002406-30-GB
- Lead Sponsor
- Conwy and Denbighshire NHS Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
Chronic renal failure classified as stage 1-4 (mild impairment to pre-end stage renal disease, Levey et al., 2003)
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
age <18yrs, previous renal replacement therapy, cardiac pacemakers, diabetes, inability to provide informed consent, current breastfeeding or pregnancy
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: To test the hypothesis that when estimating kidney function in patients with chronic renal failure, using more precise measures of muscle mass, instead of traditional indirect determinants such as sex, age, height, weight and ethnicity, will improve the accuracy of the estimation.;Secondary Objective: To determine the effects (if any) of age, gender, height and weight on renal function, which are independent of their effects on muscle mass. ;Primary end point(s): Glomerular filtration rate, serum creatinine, appendicular muscle mass, intra cellular water, demographic data (gender, age, height, weight)
- Secondary Outcome Measures
Name Time Method