How Does 4 Weeks of Increased Fast Food Intake Affect Metabolism?

Not Applicable

Completed

• Conditions: Hyper-Alimentation; Healthy
• Interventions: Procedure: Fast food arm

• Registration Number: NCT00826631
• Lead Sponsor: University Hospital, Linkoeping

Brief Summary

Objective: To study the effect of fast food-based hyper-alimentation on liver enzymes and hepatic triglyceride content (HTGC)and metabolism.

Design: Prospective interventional study with parallel control group. Setting University Hospital of Linköping, Sweden. Participants: 12 healthy men and six healthy women with a mean (SD) age of 26 (6.6) years and a matched control group.

Intervention: Subjects in the intervention group aimed for a body weight increase of 5-15% by eating at least two fast food-based meals a day with the goal to double the regular caloric intake in combination with adoption of a sedentary lifestyle for four weeks.

Main outcome measures: Weekly changes of serum aminotransferases and HTGC measured by proton nuclear magnetic resonance-spectroscopy at baseline and after the intervention.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-04
• Primary Completion: 2007-12
• Status Verified: 2009-01
• Study Completion: 2009-01
• Study First Submitted: 2009-01-21
• Study First Submitted QC: 2009-01-21
• Last Update Submitted: 2009-01-21
• Study First Posted: 2009-01-22
• Last Update Posted: 2009-01-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Healthy non-obese subjects

Exclusion Criteria

• General diseases, obesity.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Fast food arm	Fast food intake, doubling of caloric intake, in combination with sedentary behavior (no exercise)

Primary Outcome Measures

Name	Time	Method
weight gain	1 month

Trial Locations

Locations (1)

University Hospital of Linkoping; 🇸🇪 Linkoping, Sweden