Vaginal Cleaning with Chlorhexidine Solution in Preventing Post-Caesarean Section Infections
- Conditions
- Pregnancy and Childbirth
- Registration Number
- PACTR202004634203807
- Lead Sponsor
- ogah okechukwu c
- Brief Summary
The study showed that the use of 1% chlorhexidine in cleaning the vaginal before emergency caesarean section significantly reduced infectious morbidities like endometritis, decreased hospital stay. It had no effect on surgical site infection. Endo-cervical colonization by micro-organisms was significantly higher in the control 11(14%) in study group versus 41(51)% in control group, (RR) = 0.37,95% CI {0.21 – 0.64}, P 0.0001. Fowl smelling vaginal discharge was 2(2.6%) in study group versus 18(22.5%), (RR) = 9.5, 95% CI {1.30 – 64.55}, P 0.0002. Abdominal tenderness was also higher in the control group 3(3.8%) for study versus 15(30%) for control, (RR) = 2.87, 95% CI {1.00 – 8.21}, P 0.0133. Fever was also lower in the study group but was not statistically significant P value 0.286.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 168
Consented pregnant women undergoing emergency caesarean section at FETHA.
All unbooked patients undergoing caesarean section after informed consent
Patients who have been in labour for four hours or more after hospital admission.
Women with features of clinical chorioamnionitis
Women with fever (temperature = 38 degree C)
Fetal distress as an indication for CS
Placenta previa diagnosed on ultrasound
Anaemia (pack cell volume less than 21%)
Uncontrolled Gestational diabetes mellitus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endometritis. Endometritis was suggested clinically in patients with fever, fowl smelling vaginal discharge, uterine sub-involution and tenderness. It was confirmed with endo cervical swab microscopy, culture and sensitivity for all the patients
- Secondary Outcome Measures
Name Time Method Post-operative wound infection: de?ned as erythema, tenderness, purulent drainage from the incision site, with or without fever.<br>Post operative fever: de?ned as temperature equals = 38 degrees C.<br>