Effectiveness of Chlorhexidine vaginal cleansing in reducing postcaesarean surgical site infection and endometritis at two tertiary hospitals in Enugu, Nigeria: a randomized controlled trial

Phase 3

• Conditions: Pregnancy and Childbirth; Surgery; Post caesarean endometritis and wound infection

• Registration Number: PACTR202201669178899

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-01-03
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 510

Inclusion Criteria

All pregnant women who had been billed for caesarean delivery either electively or as emergency and given consent at the two Obstetrics units (ANW and Labour wards) of the two study centers were included

Exclusion Criteria

women with clinical diagnosis of chorioamnionitis
women with diagnosis of obstructed labour
women with contraindications to caesarean delivery
women with contraindication to chlorhexidine use such as history of serious allergic reaction
women with premature rupture of membranes, HIV/AIDs, diabetes mellitus and hemoglobin <10g/dl that could not be corrected before surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of women who received vaginal cleansing with chlorhexidine and had endometritis or surgical site infection or both

Secondary Outcome Measures

Name	Time	Method
proportion of babies admitted into the Newborn Special Care within 72 hours of birth for APGAR Score 7, neonatal sepsis, neonatal jaundice and other causes.