Peri-operative vaginal cleansing using 4% chlorhexidine versus 10% povidone-iodine solution to prevent post-caesarean endometritis in Ilorin: A randomized controlled study
Not Applicable
Recruiting
- Conditions
- Peuperial infectionEndometritis
- Registration Number
- PACTR202308561344907
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 136
Inclusion Criteria
Women aged =18 years scheduled for non-elective CS irrespective of the booking status.
Live intrauterine fetus (es).
Consent to participate in the study
Exclusion Criteria
Active genital warts.
Women with antepartum haemorrhage or an ongoing episode of vaginal bleeding.
Reported allergy to chlorhexidine and / or iodine containing solution.
Women previously on antibiotic therapy for more than 24hours before surgery irrespective of the indication.
Women with fetus (es) with face presentation.
Women with clinical diagnosis of chorioamionitis..
Women with diagnosed thyroid disorders or goitre on examination.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome of this study will be the incidence of endometritis (both clinical and laboratory) for women who had vaginal cleansing with 4% Chlorhexidine (experiment group) and 10% PVP-I (control). <br>
- Secondary Outcome Measures
Name Time Method secondary outcomes to be measured for the study are:<br>Presence of adverse reaction to the vaginal cleansing agent (vaginal dryness, burning sensation, vaginal itching, vulva rashes, vulva swelling, and vulva pain).<br>Clinical evidence of post-operative wound infection. <br>Relationship between risk factors for endometritis and occurrence of endometritis.<br>Neonatal outcomes especially first and fifth-minute APGAR scores as well as admission into Neonatal intensive care unit (NICU).