ISRCTN24016440终止3 期
Pragmatic cluster randomised controlled trial to evaluate the effectiveness and cost effectiveness of inhaled methoxyflurane (Penthrox) versus usual analgesia for prehospital injury and trauma
East Midlands Ambulance Service NHS Trust0 个研究点目标入组 1,040 人开始时间: 2018年1月8日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 发起方
- 入组人数
- 1,040
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Ambulance staff:
- •1. Qualified Paramedic or Emergency Medical Technician contracted by East Midlands Ambulance Service NHS Trust
- •1. Adult aged 18 years and above
- •2. Emergency attendance by ambulance paramedic or EMT
- •3. In moderate to severe pain (VNPS 4-10) due to trauma (injury) and associated pain
排除标准
- •Ambulance staff:
- •1 East Midlands Ambulance Service NHS Trust staff who are pregnant or breastfeeding
- •1. Child or young person aged under 18 years
- •2. Altered level of consciousness (Glasgow Coma Scale [GCS] <15) due to any cause including head injury, drugs, or alcohol
- •3. Suspected cardiac chest pain, sickle cell crisis
- •4. Hypersensitivity to methoxyflurane or any fluorinated anaesthetic
- •5. Malignant hyperthermia: patients with known or genetically susceptible to malignant hyperthermia or a history of severe adverse reactions in either patient or relatives
- •6. History of showing signs of liver damage after previous methoxyflurane use or halogenated hydrocarbon anaesthesia
- •7. Clinically significant renal impairment
- •8. Clinically evident cardiovascular instability
- •9. Clinically evident respiratory depression
- •10. Pregnancy and females who are breastfeeding
研究者
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