Protecting against Respiratory tract Infections through human Milk Analysis.

Recruiting

Conditions: pneumonia
Respiratory tract infection
10001708
10019815

Registration Number: NL-OMON51989

Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 1000

Inclusion Criteria

All healthy childen (and their parents) born at a minimal gestational age of 32
weeks.

Exclusion Criteria

Exclusion criteria concerning the child: - Congenital heart defect. -
Congenital lung disorder or other severe organ dysfunction. - (extreme)
prematurtity (<32 weeks GA)., Concerning the parents: - Congenital or acquired
immunodeficiency (except for allergies, eczema and hay fever). - Presence of a
medical condition or use of medication in mothers that contraindicates
breastfeeding. - Insufficient control of the Dutch Language (>B1 CEFR level).

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The amount of medically attended respiratory tract infections during the first<br /><br>year of life.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. The amount of medically attended respiratory tract infections for every<br /><br>quarter of a year during the first year of life.<br /><br>2. The amount of prescribed antibiotic treatments for respiratory tract<br /><br>infections during the first year of life.<br /><br>3. The total amount of respiratory tract infection periods during every quarter<br /><br>of a year for the first year of life.<br /><br>4. Food allergies diagnosed by a physician during the first year of life.<br /><br>5. Inhalation allergies diagnosed by a physician during the first year of life.<br /><br>6. Eczema diagnosed by a physician during the first year of life.<br /><br>7. Maternal diet.<br /><br>8. Macro- and micronutrient composition of breast milk.<br /><br>8. Microbiota composition in feces.<br /><br>9. Antibody repertoire and viral genome in saliva.</p><br>