Iron and malaria: the central role of hepcidin and macrophage functio

Recruiting

• Conditions: malaria; Plasmodium falciparum infectie; 10002086; 10002252; 10022958

• Registration Number: NL-OMON32793
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

healthy, above 18 years

Exclusion Criteria

use of iron supplementations (current or in previous 2 years)
vegan or vegetarian diet

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- the change in mRNA expression of hepcidin and other iron regulating proteins<br /><br>of the monocyte after incubation with several stimuli<br /><br>-the change in mRNA expression and protein of cytokines in monocytes after<br /><br>incubation with several stimuli<br /><br>-the change in monocyte iron content<br /><br></p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.a.</p><br>