To examine the saliva and blood for indicators of cell destruction patients with gum disease and type 2 diabetes mellitus.
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2024/06/069584
- Lead Sponsor
- DrJanani M G
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Adult males or females with healthy periodontium and with no systemic conditions
Adult males or females with a diagnosis of type 2 diabetes mellitus and periodontitis
Diabetes defined as those patients diagnosed with type 2 diabetes mellitus and are on oral hypoglycemic drugs for past one year with HbA1c lesser than equal to 10%
Periodontitis defined as those patients with periodontal probing pocket depth greater than or equal to 6mm,clinical attachment loss greater than or equal to 5mm,full mouth plaque score greater than 20%,full mouth bleeding score greater than 10% with radiographic evidence of bone loss extending to middle or apical third of the root with at least 20 natural teeth excluding third molars
Patients under immunosuppressants and or antibiotics and or anti inflammatory medications and or any drugs that could influence the periodontium for past 6 months
Pregnant or lactating mothers
History of current and past smokers
Previous history of periodontal or orthodontic therapy
Patients receiving iron replacement therapy for anemia
Patients with uncontrolled diabetes mellitus with HbA1c greater than 10%
Patients with a history of any other systemic disease other than type 2 diabetes mellitus and those patients under insulin therapy will be excluded
Subjects not willing to participate and not willing to give consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method