Magnetic Resonance Myocardial Stress Perfusion in Pediatric Patients with Cardiovascular Disease
- Conditions
- Cardiovascular DiseaseAnomalous Origin of Coronary ArteryKawasaki Disease
- Registration Number
- NCT06641843
- Lead Sponsor
- West China Second University Hospital
- Brief Summary
the goal of this observational study is to evaluate myocardial ischemia and myocardial microcirculation dysfunction in children with cardiovascular disease by myocardial stress perfusion imaging.
During their disease progress, participants will undergo myocardial stress perfusion, laboratory tests when hospitalization and follow-up, and the baseline data will be collected in the admission. all the above examination data will be analysed to identify early subclinical myocardial changes and evaluate the value of magnetic resonance myocardial stress perfusion in predicting prognosis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 240
- Patients diagnosed with cardiovascular disease, including Kawasaki disease, anomalous origin of coronary artery, postoperative congenital heart disease.
- Mental abnormalities or poor compliance ; heart, kidney and other important organs were seriously incomplete.
- MRI examination contraindications ; gadolinium contrast agent contraindications ; claustrophobia.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Major adverse cardiovscualr events 10 years after the onset Major adverse cardiovascular events including cardiac death, transient ischemic attack or stroke, myocardial infarction, arrhythmia, heart failure, severe valvular disease, percutaneous coronary intervention, coronary artery bypass graft, and other cardiovascular surgery.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
West China Second University Hospital, Sichuan University.
🇨🇳Chengdu, Sichuan, China