Magnetic Resonance Myocardial Stress Perfusion: to Improve the Myocardial Evaluation in Pediatric Patients with Cardiovascular Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Kawasaki Disease
- Sponsor
- West China Second University Hospital
- Enrollment
- 240
- Locations
- 1
- Primary Endpoint
- Major adverse cardiovscualr events
- Status
- Enrolling By Invitation
- Last Updated
- last year
Overview
Brief Summary
the goal of this observational study is to evaluate myocardial ischemia and myocardial microcirculation dysfunction in children with cardiovascular disease by myocardial stress perfusion imaging.
During their disease progress, participants will undergo myocardial stress perfusion, laboratory tests when hospitalization and follow-up, and the baseline data will be collected in the admission. all the above examination data will be analysed to identify early subclinical myocardial changes and evaluate the value of magnetic resonance myocardial stress perfusion in predicting prognosis.
Investigators
Ling-Yi Wen
Principal Investigator
West China Second University Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients diagnosed with cardiovascular disease, including Kawasaki disease, anomalous origin of coronary artery, postoperative congenital heart disease.
Exclusion Criteria
- •Mental abnormalities or poor compliance ; heart, kidney and other important organs were seriously incomplete.
- •MRI examination contraindications ; gadolinium contrast agent contraindications ; claustrophobia.
Outcomes
Primary Outcomes
Major adverse cardiovscualr events
Time Frame: 10 years after the onset
Major adverse cardiovascular events including cardiac death, transient ischemic attack or stroke, myocardial infarction, arrhythmia, heart failure, severe valvular disease, percutaneous coronary intervention, coronary artery bypass graft, and other cardiovascular surgery.