Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis
- Conditions
- Sarcoidosis
- Registration Number
- NCT01745237
- Lead Sponsor
- Duke University
- Brief Summary
The primary objective of this study was to determine the ability of cardiac magnetic resonance (CMR) to identify cardiac involvement in patients with sarcoidosis. Patients were to undergo CMR in addition to routine clinical evaluation.
- Detailed Description
In patients with sarcoidosis, cardiac death is a leading cause of mortality which may represent unrecognized cardiac involvement. Cardiovascular magnetic resonance (CMR) can detect cardiac involvement including minute amounts of myocardial damage. Therefore, the objective of this study was to determine the usefulness of CMR and compare it with standard clinical evaluation for cardiac involvement. Patients with documented extracardiac sarcoidosis or clinically suspected cardiac sarcoidosis will be enrolled.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 27000
- Biopsy proven sarcoidosis
- Suspected cardiac sarcoidosis
- Contraindication to MRI
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulmonary mortality > 1year only in subset of patients with pulmonary sarcoidosis
cardiac mortality > 1year arrhythmic death > 1year
- Secondary Outcome Measures
Name Time Method Cardiac Transplant > 1 year all-cause mortality > 1year Pulmonary Transplant > 1 year arrhythmic events > 1year PPM placement/high grade AV block > 1 year
Trial Locations
- Locations (1)
Duke University Medical Center
🇺🇸Durham, North Carolina, United States