Detecting Early Myocardial Infiltration w/Amyloid & Light Chain Deposition Disease in Multiple Myeloma Subjects

Terminated

• Conditions: Multiple Myeloma

• Registration Number: NCT01018927
• Lead Sponsor: University of Arkansas

Brief Summary

The purpose of this study is to see if MRI techniques can be used for early evaluation of cardiac amyloidosis which is sometimes seen in individuals with multiple myeloma. Cardiac amyloidosis is a medical disorder that decreases heart function.

Detailed Description

The purpose is to investigate the use of multiple newer CMR techniques for early evaluation of cardiac amyloidosis in multiple myeloma.

Study Timeline

• Study Start: 2009-06
• Study First Submitted: 2009-11-16
• Study First Submitted QC: 2009-11-24
• Study First Posted: 2009-11-25
• Status Verified: 2017-05
• Primary Completion: 2017-05-30
• Study Completion: 2017-05-30
• Last Update Submitted: 2017-05-30
• Last Update Posted: 2017-05-31

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• All races and ethnic groups
• Male and female ages 18-80 years of age
• History of multiple myeloma
• CMR study for evaluation for cardiac amyloidosis

Exclusion Criteria

• Pregnant women
• Subject with a metallic or electronic or other device that could be affected by the magnet

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
This study is to see if MRI techniques can be used for early evaluation of cardiac amyloidosis which is sometimes seen in individuals with multiple myeloma.	The time frame is five additional minutes & three additional images during and MRI.

Trial Locations

Locations (1)

University or Arkansas for Medical Sciences (UAMS); 🇺🇸 Little Rock, Arkansas, United States