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Impact of a Mobile Geriatric Team With a Pharmacist on the Optimisation of Prescriptions in Elderly Inpatients

Not Applicable
Completed
Conditions
Medication Therapy Management
Interventions
Other: Medication therapy management
Registration Number
NCT04151797
Lead Sponsor
University Hospital, Toulouse
Brief Summary

In patients aged 75 years and older, polypathology is frequent and often associated with polypharmacy. This polypharmacy coupled with a lack of proactive elderly care can sometimes lead to hospitalisation. Due to comorbidities and complex problems, management of geriatric patients usually requires a multidisciplinary approach. In Toulouse University Hospital, elderly inpatients can benefit from a geriatric assessment by a Geriatric Mobile Team. Whether this team improve the prescriptions through the advice of a clinical pharmacist has not been demonstrated yet.

Detailed Description

All participants will be identified via the geriatrician of the mobile geriatric team with the following inclusion criteria: age ≥ 75 years, ≥ 5 medications per day and being hospitalised either in emergency room, short-stay medicine unit or in a surgery department. For each patient, the pharmacist will detect potentially inappropriate prescribing (based on explicit criteria and an implicit approach) and liaise with the geriatrician for drug optimisations. The pharmaceutical advice will be added to the geriatrician's written report, and then addressed to the relevant physician. The implementation of the proposals will be evaluated immediately at the end of hospitalisation, and then reassessed three months later by calling the patient and/or his community pharmacist. A total of 250 patients will be enrolled over a 12 month-period. The evolution of potentially inappropriate prescribing will be assessed and their cost evaluated.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Patient aged 75 or older
  • Having 5 medications or more per day
  • Being hospitalised either in emergency room, short-stay medicine unit or surgery department
Exclusion Criteria
  • Patient refuses to participate
  • Patient already included in another study

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Medication therapy managementMedication therapy managementMedication therapy management by pharmacist-led medication review
Primary Outcome Measures
NameTimeMethod
Change from baseline patients' number of potentially inappropriate prescription at the patient discharge after optimization by a mobile geriatric team with pharmacistMonth 0 and max Month 2 (At the patient discharge)

number of potentially inappropriate prescribing per patient before (month 0) and after the intervention of the mobile geriatric team (at the patient discharge)

Secondary Outcome Measures
NameTimeMethod
Change from baseline patients' number of potentially inappropriate prescription at 3 months after optimization by a mobile geriatric team with pharmacistMonth 0, Month 3

number of potentially inappropriate prescribing per patient before (month 0) and after the intervention of the mobile geriatric team (month 3)

Change from baseline patients' number with at least one potentially inappropriate drug at 3 months after optimization by a mobile geriatric team with pharmacistMonth 0, Month 3

number of patients with at least one potentially inappropriate drug before (month 0) and after the intervention of the mobile geriatric team (month 3)

Change from baseline ratio of potentially inappropriate drug per patient at 3 months after optimization by a mobile geriatric team with pharmacistMonth 0, Month 3

ratio of potentially inappropriate drug per patient before (month 0) and after (month 3) the intervention of the mobile geriatric team.

Change from baseline mean number of medications per patient at 3 monthsMonth 0, Month 3

Mean number of medications per patient

realisation of a pharmacist-led medication review in primary careMonth 3

Number of pharmacist-led medication review performed in primary care at 3 months

number of falls 3 months after pharmacist-led medication reviewMonth 3

Number of falls

mortality 3 months after pharmacist-led medication reviewMonth 3

Number of deaths

re-hospitalisation, including emergency room transfersMonth 3

Number of non-scheduled hospitalisations (including emergency department transfers)

The nursing home transfersMonth 3

Number of nursing home transfers

Trial Locations

Locations (1)

Toulouse University Hospital

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Toulouse, Occitanie, France

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