NL-OMON31738尚未招募不适用
Doxycycline and airway inflammation in COPD A randomised placebo controlled cross-over trial in patients with GOLD III COPD - Doxycycline and airway inflammation in COPD
Medisch Centrum Alkmaar0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •GOLD II COPD (FEV1/FVC < 70%; 50% < FEV1 < 80% predicted).
- •Stable disease (no exacerbations in the last 3 months).
- •Age >40 yrs.
- •Written informed consent.
排除标准
- •Infections and/or use of antibiotics in the last month.
- •Allergy for tetracyclines or a history of substantial side-effects.
- •Active respiratory diseases other than COPD (e.g. sarcoidosis, tuberculosis, lung cancer, bronchiectasis).
- •Signs and/or symptoms consistent with an acute exacerbation of COPD (AECOPD), such as increase in dyspnea, increase in sputum volume or change of sputum color from mucoid to purulent.
- •Signs and/or symptoms of a current respiratory or non-respiratory infection.
- •Use of oral or intravenous corticosteroids or other immunosuppressive drugs within the last month.
研究者
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