Influence of Aerobic Exercise on cognitive function in Depressed elderly

Not Applicable

• Conditions: Depression; Women; Aged; F01.145.126.350; M01.975; M01.060.116.100

• Registration Number: RBR-2nnywk
• Lead Sponsor: Centro de Ciências da Saúde da Universidade Federal de Pernambuco

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-21
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Elderly persons previously diagnosed by physicians qualified both in the public and private network of Recife, PE, Brazil; who are 60 years of age or over; have not exercised for at least six months; sign the informed consent form.

Exclusion Criteria

To have acute musculoskeletal pain, interfering in the performance of the tests and in the training; history and sequelae of neurodegenerative diseases; express the desire to stop participating in the research.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The expected outcome 1 is the improvement of cognitive functions in depressed elderly women when compared to pre and post training (after 24 training sessions), evaluated through: Stroop test (selective attention) will be taken into account the number of errors and the time spent; verbal fluency test (if we consider the number of fruits said); labyrinth test (navigation capability) will be used in the evaluation of the planning and execution time; dual task test (accomplishment of a motor task aligned with a cognitive task) what will be considered is the execution time.;The expected outcome 2 is the improvement of Brain Derived Neurotrophic Factor (BDNF) levels (collected 5 ml of blood per arm puncture) in depressed women when compared to pre and post training (after 24 training sessions).

Secondary Outcome Measures

Name	Time	Method
The expected outcome 1 is lower depressive scores in the Geriatric Depression Scale (GDS-30), with a score:> 10 depression representation, a score between 11-20 = moderate depression and a score> 20 severe depression, in depressed women when compared pre and post training (after 24 training sessions).;The expected outcome 2 is the improvement in the cardiorespiratory capacity of the depressive elderly, when compared to pre and post training (after 24 training sessions), evaluated through the submaximal test for elderly with mood disorder (OLIVEIRA et al., 2012).