Effects of Aerobic Exercise on Cognitive Function and Brain-derived Neurotrophic Factor in Young Adults

Not Applicable

Completed

• Conditions: Physical Conditioning, Human; Cognition
• Interventions: Behavioral: High intensity aerobic exercise; Behavioral: Low intensity aerobic exercise

• Registration Number: NCT02075944
• Lead Sponsor: University of Southern Denmark

Brief Summary

The present study will investigate the effects of aerobic exercise on cognition and growth factors including brain-derived neurotrophic factor (BDNF) in young adults aged 15-21 years. The included subjects will be randomized to three different groups including one control group and two exercise groups. Subjects randomized to the exercise groups will complete 30 minutes of aerobic exercise 3 times a week for 9 weeks incorporating low (group I) or high (group II) intensity aerobic exercise. The exercise will be conducted as running or indoor cycling (supervised). At baseline and 9-weeks follow-up all subjects will complete two cognitive tests (measures of concentration and sustained attention), a maximal cycling test (direct measures of VO2max), an intelligence quotient test, anthropometric measures, fasting blood samples and blood samples immediately following the cycling test. The blood samples will be analyzed for growth factors including BDNF and metabolic factors.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02
• Study First Submitted: 2014-02-27
• Study First Submitted QC: 2014-02-27
• Study First Posted: 2014-03-03
• Status Verified: 2014-06
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Last Update Submitted: 2014-06-25
• Last Update Posted: 2014-06-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

• age 15-21

Exclusion Criteria

• injury preventing one from being physically active

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
High intensity aerobic exercise	High intensity aerobic exercise	30 minutes of high intensity aerobic exercise 3 times a weeks for 9 weeks - incorporation interval training
Low intensity aerobic exercise	Low intensity aerobic exercise	30 minutes of low intensity aerobic exercise 3 times a weeks for 9 weeks

Primary Outcome Measures

Name	Time	Method
The Flanker Task	9 weeks
The AX-Continuous Performance test	9 weeks
Brain-derived neurotrophic factor	9 weeks

Secondary Outcome Measures

Name	Time	Method
Intelligence quotient	9 weeks

Trial Locations

Locations (1)

University of Southern Denmark; 🇩🇰 Odense, Denmark