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Relation of MUscular contractions to mechanical STrains in the human tibia during different locomotive activities

Conditions
Healthy Volunteers
Registration Number
DRKS00004207
Lead Sponsor
Deutsches Zentrum für Luft- und RaumfahrtInstitut für Luft- und RaumfahrtmedizinWeltraumphysiologie
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Male
Target Recruitment
5
Inclusion Criteria

•five male healthy subjects
•age between 20 and 55 years
•Body mass index (BMI): 20 -30 kg/m2
•signed consent form

Exclusion Criteria

• Apart from the PI of the study, Prof. Jörn Rittweger, no further co-workers of DLR or Cologne University Hospital, or financially dependent persons may participate as test subjects
•corticalis-diameter under 4 mm at site of planned screw insertion
•muscle or joint disorders
•fractures of the lower extremity in the last 12 months
•metall-implants
•participation in a different clinical study within 2 months prior to start of study
•decreased blood-coagulation
•unwanted reactions on local anaesthetic in the past
•operations on the tibia in the last 12 months
•Any other condition that leads to exclusion from the study in the eyes of the clinical investigator

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Assessment of the influence of muscle force and gravitational force on the deformation of bone (tibia) with a vicon-camerasystem, motion capturing, electromyography, ultrasound und several devices for force measurements.
Secondary Outcome Measures
NameTimeMethod
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