Impact of carbohydrate co-ingestion on the post-prandial anabolic response of protein in young and elderly me
Completed
- Conditions
- 10018424spiermetabolismenvt
- Registration Number
- NL-OMON35860
- Lead Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 48
Inclusion Criteria
24 healthy, young male subjects (18-30 y)
24 healthy, elderly male subjects (70-85 y)
Exclusion Criteria
• Diabetes
• Obesity (BMI > 30 kg/m2)
• All co-morbidities interacting with mobility and muscle metabolism (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders).
• Hypertension (according to WHO criteria)
• Use of anticoagulants, blood diseases, allergy for lidocain
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Muscle protein synthesis rate, expressed as fractional synthetic rate (FSR). </p><br>
- Secondary Outcome Measures
Name Time Method <p>Rate of protein digestion and absorption, whole body protein balance and<br /><br>microvascular perfusion and diameter. </p><br>