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A study examining the effect of consuming foods containing probiotics on anxiety and depressive symptoms : A non-randomized and open trial

Phase 1
Conditions
Schizophrenia
Registration Number
JPRN-UMIN000025417
Lead Sponsor
Hokkaido University Hospital Department of Psychiatry and Neurology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

1. Subjects who have uncontrolled diseases or untreatable malignant tumor. 2. Subjects who have cognitive impairment disorder or disturbance of consciousness 3. Subjects who have severe idea of suicide or symptoms that require to urgent treatment 4. Subjects who want to take medications for anxiety or depressive symptoms 5. Subjects who have taken antidepressants in the last month 6. Subjects whose daily intake of food or supplements includes Bifidobacterium 7. Subjects who daily consume a high amount of alcohol (more than 500 ml of beer per day) 8. Subjects who have mental disorders not including schizophrenia, mood disorder, or anxiety disorder 9. Subjects who are deemed to be inappropriate to participate in this study, by the physician in charge of this study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The correlation coefficient between increase in the Bifidobacterium occupancy rate and decrease in HADS score for 4 weeks in low Bifidobacterium group
Secondary Outcome Measures
NameTimeMethod
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