The effect of curcumin supplementation in the treatment of patients with ulcerative colitis

Phase 3

Recruiting

• Conditions: lcerative colitis.; Ulcerative colitis

• Registration Number: IRCT20180207038664N1
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 May 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Ulcerative colitis, confirmed by histopathology
The severity of the disease is mild to moderate
Patients without current diagnosis of other inflammatory, autoimmune and inclusive disease( including cancer, kidney disease, rheumatoid arthritis, liver disease, AIDS, and cardiovascular disease)
The age range is between 17-70 years
Tendency to participate in the study
No changes in the type and amount of drug in the past month
The patient should not be pregnant or breastfeeding

Exclusion Criteria

The patient is in the acute phase of the disease
Reluctance to continue cooperation in this research
History of large gastrointestinal surgery (except appendectomy, Cholecystectomy and hemorrhoidectomy)
Smoking, alcohol and drug abuse
Patients with gallstones or any disorder of the gallbladder, bladder stones

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum hs-CRP. Timepoint: The beginning of the study- The end of the study. Method of measurement: ELISA.;Serum TNF-a. Timepoint: The beginning of the study- The end of the study. Method of measurement: ELISA.;Serum ESR. Timepoint: The beginning of the study- The end of the study. Method of measurement: Westergren's Method.;Stool frequency per day. Timepoint: The beginning of the study- The end of the study. Method of measurement: Mayo Score.;Frequency of rectal bleeding per day. Timepoint: The beginning of the study- The end of the study. Method of measurement: Mayo Score.