Clinical Effects of Highly Absorptive Curcumin (curcurouge) on knee osteoarthritis
Phase 3
Recruiting
- Conditions
- knee osteoarthritisknee joint medial typeD020370
- Registration Number
- JPRN-jRCTs051230130
- Lead Sponsor
- akagawa Yasuaki
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
1) Medial knee osteoarthritis and KL classification
I or II or III, 2) over 40 years. 3) VAS before starting is more than 30/100, 4) consent of patient , 5)
outpatient
Exclusion Criteria
1)the patients who take more than 2 kinds of anti-coagulant drugs 2)Severe renal dysfunction or dialysis 3)severe liver dysfunction or liver cirrhosis 4)severe cardiovas
cular diseases 5)severe cerebrovascular dysfuncti
on 6)severe diabetes mellitus 7)curcumin abuse
patients 8)previous knee surgery or intraarticular i
njection for experimental period or steroid intraart
icular injection before 2 months or steroid oral int
ake before 4 weeks 9)patient who must be exclud
ed by the scientific responsible doctor
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method JKOM, VAS, JOA knee OA score, KOOS Japanese version,dependence of N<br>SAIDs
- Secondary Outcome Measures
Name Time Method Time up and go, knee range of motion biochemic<br>al analysis of blood, responder rate of OMERACT-OARSI