Effects of metformin on human gut bacteria
- Conditions
- Young healthy menMedDRA version: 20.0Level: PTClassification code 10062192Term: Metabolic function test normalSystem Organ Class: 10022891 - InvestigationsMedDRA version: 20.0Level: PTClassification code 10053075Term: Microbiology testSystem Organ Class: 10022891 - InvestigationsTherapeutic area: Body processes [G] - Physiological processes [G07]
- Registration Number
- EUCTR2015-000199-86-DK
- Lead Sponsor
- niversity of Copenhagen, The Novo Nordisk Foundation Center For Basic Metabolic Research, section of Metabolic Genetic
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- Not specified
Male
HbA1c < 5.7 % (39 mmol/mol) at time of screening; i.e. normal glucose metabolism
Caucasian (self-report of parental ethnicity)
Age 18 - 35 years
Weight stabile with 18.5 kg/m2 < BMI < 27.0 kg/m2
Normal kidney function as evaluated by normal p-creatinine for age
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 25
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Oral intake of any form of prescribed medication two months prior to recruitment
Chronic or acute illness
Previous gastro-intestinal operation excluding appendicitis
Any other significant medical reason for exclusion as determined by the investigator
Unable to give informed consent
Need of medical treatment during the study period
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method