Effect of adding clonidine versus placebo to the standard treatment in patients with bipolar disorder during manic episode

Phase 3

Recruiting

• Conditions: Bipolar disorder during manic episode.; Bipolar disorder, current episode hypomanic; F31.0

• Registration Number: IRCT20120215009014N295
• Lead Sponsor: Hamedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

Age of 18 to 65 years
Bipolar disorder during manic episode
Need hospitalization
Young score of 20 or higher

Exclusion Criteria

Pregnancy or breastfeeding
Sensitivity to lithium or alpha-2 adrenergic receptor stimulants
History of suicide, homicide, or suicidal intention
History of drug abuse
History of using anticholinergic or antidepressant three-cyclic drugs

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessing sleep quality. Timepoint: Before the intervention and 12 and 24 days after the intervention. Method of measurement: By using Pittsburg Sleep Quality Index (PSQI).;Assessing the cognitive status. Timepoint: Before the intervention and 12 and 24 days after the intervention. Method of measurement: By using Montreal Cognitive Assessment (MOCA) and Mini Mental State Examination (MMSE).