NL-OMON49449
Completed
Not Applicable
The impact of norepinephrine on the dynamic aspect of brain activity - Dyn-Neuromod
niversiteit Leiden0 sites36 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- scientific investigation of healthy subjects
- Sponsor
- niversiteit Leiden
- Enrollment
- 36
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Trial is onging in other countries
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy adult subjects with no history of neurological disorder/disease and no
- •counter\-indications to 3 Tesla MRI or to atomoxetine, and no personal
- •relationship with the researchers will be included in this study. All
- •participants will be right\-handed with normal vision or contact lenses.
Exclusion Criteria
- •Significant history of head trauma, premature birth, learning disabilities,
- •neurological or psychiatric illness. Heart arrhythmia, glaucoma, congenital eye
- •diseases, hyperopia, myopia, hypertension and use of anti\-depressants or
- •psychotropic medication and possible pregnancy (in adult females). MRI
- •contra\-indications, including metal implants and claustrophobia. Smoking more
- •than five cigarettes a day \- to avoid nicotine withdrawal effects during the
- •study. Alcohol consumption \< 24 hours before study, caffeine consumption \< 3
- •hours before study.
- •These criteria will be assessed by a self\-report questionnaire administered
- •during pre\-screening.
Outcomes
Primary Outcomes
Not specified
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