A randomised clinical trial comparing peri-discharge management of Acute Decompensated Heart Failure with usual clinical care in terms of rates of death, rates of hospitalisation, health care utilisation, and cost-effectiveness.
Not Applicable
Active, not recruiting
- Conditions
- Heart FailureCardiovascular - Other cardiovascular diseases
- Registration Number
- ACTRN12614001030662
- Lead Sponsor
- Christchurch Heart Institute. University of Otago
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 450
Inclusion Criteria
Patients aged >18 year, living independently and able to provide informed consent, admitted with ADHF as evidenced by typical clinical features plus either radiological evidence of Heart Failure or an NTproBNP level >1000pg/ml.
Exclusion Criteria
A primary diagnosis of acute coronary syndrome (ACS), myocarditis/pericarditis, pericardial constriction, a life expectancy due to non-cardiac disease of <6 months, concurrent severe hepatic or pulmonary disease ,severe renal impairment (plasma creatinine >250 micro mol/L), severe valvular disease requiring surgery, severe aortic stenosis (valve area <1cm^2), or HF due to mitral stenosis, or a patient under consideration for cardiac transplantation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first Heart Failure readmission or all cause death within 180 days[ 180 days]
- Secondary Outcome Measures
Name Time Method Time to first Heart Failure readmission or all cause death within 180 days[ 180 days];Time to first Heart Failure readmission within 30 days; within 90 days; and within 180 days.[ within 30 days; within 90 days; and within 180 days.];Time to all cause death within 30 days; within 90 days; and within 180 days[ within 30 days; within 90 days; and within 180 days]