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A Study of the Safety of Atezolizumab in Participants With Locally Advanced or Metastatic Non Small Cell Lung Cancer in Argentina

Completed
Conditions
Carcinoma, Non-small-cell Lung
Registration Number
NCT03321695
Lead Sponsor
Hoffmann-La Roche
Brief Summary

This is a study of the safety and effectiveness of atezolizumab in participants with metastatic non-small cell lung cancer (NSCLC) who have disease progression during or following platinum-containing chemotherapy. Participants also will have progressed on an appropriate approved targeted therapy if their tumor has epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase (ALK) gene abnormalities treated in common clinical practice settings in Argentina.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
44
Inclusion Criteria
  • Signed an informed consent form submitted to the Administración Nacional de Medicamentos Alimentos y Tecnología Médica (ANMAT)
  • Locally advanced or metastatic (Stage IIIB, Stage IV, or recurrent) non-small cell lung cancer (NSCLC)
  • Have received at least one dose of atezolizumab as per local label and clinical practice
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Exclusion Criteria
  • Contraindicated atezolizumab therapy
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Percentage of Participants With Adverse EventsUp to approximately 2 years
Secondary Outcome Measures
NameTimeMethod
Overall Survival (OS)Up to approximately 2 years
Duration of Response (DOR)Up to approximately 2 years
Progression-Free Survival (PFS)Up to approximately 2 years
Percentage of Participants With a Confirmed Objective Response (ORR) of Complete Response (CR) or Partial Response (PR)Up to approximately 2 years

Trial Locations

Locations (1)

Productos Roche S.A. Quimica e Industrial, División Farmacéutica

🇦🇷

Buenos Aires, Argentina

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