Ventriculomegaly and Gait Disturbance in the Senior Population in the Region of Västerbotten

Completed

• Conditions: Idiopathic Normal Pressure Hydrocephalus (INPH); Brain Diseases; Dementia; Gait Disorders, Neurologic; Hydrocephalus, Normal Pressure; Central Nervous System Diseases

• Registration Number: NCT05204745
• Lead Sponsor: Umeå University

Brief Summary

Idiopathic normal pressure hydrocephalus (INPH) is a treatable disease of the elderly, typically causing gait impariment, dementia and urinary incontinence. The objective of this study is to make an epidemiological survey of INPH in Umeå, Sweden. Subjects with self-perceived gait impairments will be identified through a questionnaire. They will go through clinical examinations and have an MRI of the brain. A control population will also be investigated to enable comparisons between the populations. The main hypothesis is that the prevalence of INPH in the population is higher than what is previoulsy known.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-14
• Study First Submitted: 2021-10-01
• Primary Completion: 2021-12-22
• Study Completion: 2021-12-22
• Status Verified: 2022-01
• Study First Submitted QC: 2022-01-10
• Last Update Submitted: 2022-01-10
• Study First Posted: 2022-01-24
• Last Update Posted: 2022-01-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6500

Inclusion Criteria

• Living in Umeå, Sweden.

Exclusion Criteria

• Age <65 or >84 years when the questionnaire was sent out.
• Death at the time for the clinical evaluation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of participants with Idiopathic Normal Pressure Hydrocephalus	Through study completion, an average of approximately 1 month.	Diagnosis of INPH based on clinical evaluation and MRI.

Trial Locations

Locations (1)

Norrlands Universitetssjukhus; 🇸🇪 Umeå, Västerbotten, Sweden