ISRCTN33288337已完成未知
The first Therapeutic Interventions in Malignant Effusion trial
niversity of Oxford (UK)0 个研究点目标入组 320 人开始时间: 2006年4月19日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 320
研究概览
简要总结
2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/26720026 results
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Clinically confident diagnosis of malignant pleural effusion requiring pleurodesis
- •Definitions:
- •1.1. Histologically proven pleural malignancy
- •1.2. Typical features of pleural malignancy seen on direct vision during thoracoscopy
- •1.3. Pleural effusion in the context of histologically proven cancer elsewhere
- •2. Written informed consent
- •3. Expected survival more than one month
排除标准
- •1. Age less than 18 years
- •2. Primary lymphoma or small cell lung carcinoma
- •3. Patients who are pregnant or lactating
- •4. Inability to give informed consent
- •5. History of gastrointestinal (GI) bleeding or of untreated peptic ulceration
- •6. Known sensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) or opiates
- •7. Hypercapnic ventilatory failure
- •8. Known intravenous drug abuse
- •9. Severe renal or liver disease
- •10. Known bleeding diathesis
- •11. Warfarin therapy which must be continued
- •12. Current or recent (within two weeks) corticosteroid steroid therapy
研究者
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