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临床试验/EUCTR2014-000574-19-IT
EUCTR2014-000574-19-IT进行中(未招募)1 期

Experimental study for the evaluation of the effect of radioactive iodine therapy on free thyroxine circulating levels after oral administration of sodium levo-thyroxine in patients thyroidectomized for differentiated thyroid cancer . - Free thyroxine circulating levels after radioactive iodine therapy

AZIENDA OSPEDALIERO-UNIVERSITARIA DI PARMA0 个研究点目标入组 30 人开始时间: 2014年2月20日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • -Adult patients thyroidectomized for differentiated thyroid cancer
  • -Written informed consent to partecipate in the study
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 20
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range 10

排除标准

  • -Patients who will undergo radioactive iodine therapy in a hypothyroid state
  • -Inflammatory bowel diseases
  • -Malabsorption, chronic gastritis
  • -Treatment with estrogens, selective estrogen receptor modulators, drugs known to modify Levo-thyroxine absorption (i.e.: proton pump inhibitors, resins, iron, sucralfate, calcium, alluminum, chemotherapy, immunosuppressive therapy)
  • -Previous radiotherapy or radioactive iodine therapy
  • -Pregnancy
  • -Organ failure or other disease known to limit life expectancy
  • -History of chronic inflammatory/infectious/autoimmune diseases
  • -Any abnormality found during clinical examination at the screening visit, which according to the opinion of the investigator may be harmful for the patient in order to complete the study
  • -History of low compliance or psychiatric illness or any other condition which make the study inappropriate

研究者

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