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Onderzoek naar het vrijwillig adem inhouden tijdens de bestraling voor alvleesklierkanker voor nauwkeuriger bestraling

Conditions
Resectable pancreatic cancer, borderline resectable pancreatic cancer, irresectable pancreatic cancer, radiochemotherapy, breath hold technique for radiation, fiducial markers
Registration Number
NL-OMON25458
Lead Sponsor
Academic Medical Center, Amsterdam
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
10
Inclusion Criteria

Patients with pancreatic cancer, locally advanced or (borderline) resectable status, who are treated with radio(chemo)therapy;

- WHO performance status of 0-2;

Exclusion Criteria

- Inability to undergo the additional treatment planning CT scan and fluoroscopy;

- Serious lung condition precluding breath-hold

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Comparison of preparatory, inter and intra fraction tumour motion between free breathing and breath hold conditions
Secondary Outcome Measures
NameTimeMethod
- Feasibility of irradiation in breath hold conditions<br /> <br>- Calculation of change in margins in breath hold conditions compared to free breathing<br /> <br>- Calculation of potentially resulting changes in normal tissue complication probability (NTCP)
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