Acute Effects of HIIT vs. MICT on HRV

Not Applicable

Recruiting

• Conditions: Myocardial Infarction
• Interventions: Other: Type of Exercise

• Registration Number: NCT06437145
• Lead Sponsor: University Medical Centre Ljubljana

Brief Summary

Heart rate variability (HRV) is impaired in patients after myocardial infarction. Most studies so far have proved chronic beneficial effects of different types of exercise on HRV parameters. Data on acute effects of different types of exercise training (e.g. high intensity interval training \[HIIT\] and moderate intensity continuous training \[MICT\]) is scarce.

Patients in the study will perform both HIIT and MICT in a random order and in-between break of at least 48 hours. A 5-minute high resolution ECG recording will be performed before and immediately after both HIIT and MICT.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-02-15
• Study First Submitted: 2024-04-16
• Status Verified: 2024-05
• Study First Submitted QC: 2024-05-25
• Last Update Submitted: 2024-05-25
• Study First Posted: 2024-05-31
• Last Update Posted: 2024-05-31
• Primary Completion: 2024-06-01
• Study Completion: 2024-06-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• myocardial infarction in last 120 days
• sinus rhythm

Exclusion Criteria

• contraindications for exercise training
• uncontrolled dysrhythmias
• Heart Failure NYHA IV stage
• cognitive impairment
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
High intensity interval training (HIIT)	Type of Exercise	The high-intensity interval training session consists of 5-min warm-up and 5-min cool-down periods. The main part has 7 cycles. Each cycle consists of 1.5 min of 80-90% of HRpeak and 3 min of 65-70% of HRpeak.
Moderate intensity continuous training (MICT)	Type of Exercise	The moderate-intensity continuous training session consists of 5 min warm-up and 3-min cool down period. The main part consists of 32 min of 75% of HRpeak.

Primary Outcome Measures

Name	Time	Method
HF parameter	5-minutes high resolution ECG recording before and after an exercise session	High frequency domain of the HRV

Secondary Outcome Measures

Name	Time	Method
RMSSD	5-minutes high resolution ECG recording before and after an exercise session	Root mean square of successive RR interval differences
LF parameter	5-minutes high resolution ECG recording before and after an exercise session	Low frequency domain of the HRV
pNN50	5-minutes high resolution ECG recording before and after an exercise session	Percentage of successive RR intervals that differ by more than 50 ms
SDNN	5-minutes high resolution ECG recording before and after an exercise session	Standard deviation of NN intervals

Trial Locations

Locations (1)

University Medical Centre Ljubljana; 🇸🇮 Ljubljana, Slovenia