Efficacy of a Combination of Ketamine and Morphine for Intravenous Patient Controlled- Analgesia in Upper Abdominal Surgery: A Prospective, Double-blind, Randomized Controlled Trial

Phase 3

Completed

• Conditions: Patients undergoing elective upper abdominal surgery; Ketamine, Morphine, Upper abdominal surgery, Intravenous patient-controlled analgesia

• Registration Number: TCTR20210708002
• Lead Sponsor: Khon kaen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-08-31
• Study Start: 2021-07-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 67

Inclusion Criteria

Patients 18-65 years of age who were classified as ASA physical status class I-II

Exclusion Criteria

Patients who had a history of chronic opioid use, had a history of chronic pain, had undergone a neuraxial block, had allergies to morphine or ketamine, suffered from psychiatric disorders, or were unable to operate the IV-PCA were excluded from the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cumulative morphine consumption 48 hours Mg of morphine by IV PCA history device

Secondary Outcome Measures

Name	Time	Method
pain score (at rest and during movement) at 1, 4, 12, 24, 36, and 48 hour post operative pain score at 1, 4, 12, 24, 36, and 48 hour post operative