Energy Turnover and Appetite

Not Applicable

Completed

• Conditions: Obesity

• Registration Number: NCT05365685
• Lead Sponsor: University Hospital, Clermont-Ferrand

Brief Summary

The aim of the study is to compare the effect of a low versus moderate versus high energy turnover on energy intake, appetite and food reward, in adolescents with obesity. 18 adolescents with obesity will then complete three experimental sessions in a randomized order: low, high and moderate Energy turnover.

Detailed Description

A total of 18 adolescents with obesity, aged 12-16 years olds will complete three experimental sessions in a randomized order: i) low energy turnover; ii) Moderate energy turnover and ; iii) High energy turnover. Their ad libitum energy intake at dinner will be assessed through an ad libitum buffet-type meal, their food reward assessed right before the dinner meal and their appetite sensation at regular intervals during the day.

Study Timeline

• Status Verified: 2022-03
• Study First Submitted: 2022-03-29
• Study First Submitted QC: 2022-05-04
• Study First Posted: 2022-05-09
• Study Start: 2022-08-27
• Primary Completion: 2022-10-29
• Study Completion: 2023-11-08
• Last Update Submitted: 2025-07-09
• Last Update Posted: 2025-07-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• BMI percentile > 97th percentile according to the french curves.
• ages 12-16 years old
• Signed consent form
• being registered in the national social security system
• no contraindication to physical activity

Exclusion Criteria

Previous surgical interventions that is considered as non-compatible with the study.

• Diabetes
• weight loss during the last 6 months
• cardiovascular disease or risks

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Energy intake measured during an ad libitum buffet meal (in kcal).	it will be assessed at dinner baseline	food intake will be measured ad libitum during a dinner buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using a nutritional software.

Secondary Outcome Measures

Name	Time	Method
Hunger feelings	immediately after breakfast/lunch/dinner on day 1	hunger area under the curve will be assessed using visual analogue scale through a the day
Food reward	it will be assessed at dinner baseline	: The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ). Briefly, the LFPQ provides measures of the wanting and liking for an array of food images, varying in both fat content and taste.

Trial Locations

Locations (1)

CHU clermont-ferrand; 🇫🇷 Clermont-Ferrand, France