Effect of Prophylactic NSAID Drops on Cystoid Macular Edema After Cataract Surgery Using Optical Coherence Tomography
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Macular Edema, Cystoid
- Sponsor
- Queen's University
- Enrollment
- 98
- Locations
- 1
- Primary Endpoint
- Degree of cystoid macular edema by means of OCT (total macular volume) measurements
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The study will evaluate the efficacy of prophylactic administration of the topical nonsteroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.5% (Acular®) on cystoid macular edema (CME) in patients having undergone cataract surgery. CME is the most frequent cause of decreased vision after uncomplicated cataract surgery and can result in irreversible sight reduction. The investigation will involve a comparison arm and a treatment arm with both sets of patient populations being evaluated for CME with ophthalmologic examinations and optical coherence tomography (OCT) measurements. The objective is to elucidate the role of NSAID drops in preventing CME after cataract surgery.
Investigators
Dr. Sherif R El-Defrawy
Principal Investigator
Queen's University
Eligibility Criteria
Inclusion Criteria
- •First cataract surgery (i.e., first eye).
Exclusion Criteria
- •hypersensitivity to the NSAID drug class,
- •pregnancy.
Outcomes
Primary Outcomes
Degree of cystoid macular edema by means of OCT (total macular volume) measurements