跳至主要内容
临床试验/NCT00335439
NCT00335439已完成不适用

Effect of Prophylactic NSAID Drops on Cystoid Macular Edema After Cataract Surgery Using Optical Coherence Tomography

Queen's University2 个研究点 分布在 1 个国家目标入组 98 人开始时间: 2006年6月最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
98
试验地点
2
主要终点
Degree of cystoid macular edema by means of OCT (total macular volume) measurements

研究概览

简要总结

The study will evaluate the efficacy of prophylactic administration of the topical nonsteroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.5% (Acular®) on cystoid macular edema (CME) in patients having undergone cataract surgery. CME is the most frequent cause of decreased vision after uncomplicated cataract surgery and can result in irreversible sight reduction. The investigation will involve a comparison arm and a treatment arm with both sets of patient populations being evaluated for CME with ophthalmologic examinations and optical coherence tomography (OCT) measurements. The objective is to elucidate the role of NSAID drops in preventing CME after cataract surgery.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • First cataract surgery (i.e., first eye).

排除标准

  • hypersensitivity to the NSAID drug class,
  • pregnancy.

结局指标

主要结局

Degree of cystoid macular edema by means of OCT (total macular volume) measurements

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Sherif R El-Defrawy

Principal Investigator

Queen's University

研究点 (2)

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