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Observational Registry Study of Chinese Patients Treated With Revlimid (Lenalidomide)

Terminated
Conditions
Multiple Myeloma
Interventions
Registration Number
NCT01947309
Lead Sponsor
Celgene
Brief Summary

The primary objective of this study is to document efficacy and safety data in a real-world setting of Chinese multiple myeloma patients who have received at least one prior therapy treated with REVLIMID (lenalidomide).

Detailed Description

This registry is prospective, multi-center, observational study and will collect efficacy and safety data on multiple myeloma adult patients who have received at least one prior therapy and take REVLIMID as part of standard care associated with patients' treatment in order to characterize the use, efficacy and outcomes of REVLIMID treatment.

The registry will capture data from 600 patients being prescribed REVLIMID in specified hospitals and all patients will be followed in the registry for two years after enrollment of the last patient.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
176
Inclusion Criteria
  • Must understand and voluntarily sign written informed consent At least 18 years old at the time of signing informed consent Diagnosed with Multiple Myeloma Must have received at least one prior Multiple Myeloma treatment at the time of signing informed consent
Exclusion Criteria
  • None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Multiple Myeloma Patients Treated with Revlimid (lenalidomide)Revlimid (lenalidomide)Single Cohort of Multiple Myeloma Patients Treated with Revlimid
Primary Outcome Measures
NameTimeMethod
Progression Free Survival (PFS)2 years after enrollment of last patient

Assessment of PFS using IMWG Uniform Response Criteria

Response Rates2 years after enrollment of last patient

Assessment of Response Rates (CR, VGPR, PR) using IMWG Uniform Response Criteria

Secondary Outcome Measures
NameTimeMethod
Overall Survival (OS)Two years after last patient enrolled
Time to Response (TTR) and Duration of Response (DOR)Two years after last patient enrolled
Duration of Treatment with RevlimidTwo years after last patient enrolled.

Reason for dose interruption/reduction of REVLIMID, if this occurs. Reason for discontinuation of REVLMID

Safety Profile of RevlimidTwo years after last patient enrolled

All Adverse Events (AEs) and occurrence of second primary malignancies (SPM)

Trial Locations

Locations (17)

Beijing Hospital

🇨🇳

Beijing, China

Xiangya Hospital Central-South University

🇨🇳

Changsha, China

Shanghai Changzhen Hospital

🇨🇳

Shanghai, China

The Affiliated Hospital of Mecical College Qingdao University

🇨🇳

Qingdao, China

Peking Chao-Yang Hospital

🇨🇳

Beijing, China

People's Liberation Army Hospital 307

🇨🇳

Beijing, China

Peking University People's Hospital

🇨🇳

Beijing, China

The Second Affiliated Hospital Of China Medical University

🇨🇳

Shenyang, China

Wuhan Union Hospital of Tongji Medical College of Huazhong University of Science & Technology

🇨🇳

Wuhan, China

The Fisrt Hospital Of Jilin University

🇨🇳

Changchun, China

NanFang Hospital of China Southern Medical University

🇨🇳

Guangzhou, China

The First Affliated Hospital of Anhui Medical University

🇨🇳

Hefei, China

The First Affiliated Hospital of Suzhou University

🇨🇳

Suzhou, China

People's Hospital of Xinjiang Uygur Autonomous Region

🇨🇳

Urumqi, China

Tongji Medical College Huazhong University of Science & Technology

🇨🇳

Wuhan, China

Xinqiao Hospital, 3rd Military Medical University

🇨🇳

Chongqing, China

Qilu Hospital of Shandong University

🇨🇳

Jinan, China

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