MedPath

Inaticabtagene Autoleucel Injection Treatment for Adult Relapsed or Refractory Acute Lymphocytic Leukemia

Not yet recruiting
Conditions
B-cell Acute Lymphoblastic Leukemia
Registration Number
NCT06450067
Lead Sponsor
Juventas Cell Therapy Ltd.
Brief Summary

This clinical trial is a non-interventional, observational, multicenter, post-marketing real-world study to evaluate the efficacy and safety of Inaticabtagene Autoleucel Injection in Chinese adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia.

Detailed Description

The study is a non-interventional, observational, multicenter, post-marketing real-world study, and its objective is to evaluate the efficacy and safety of Inaticabtagene Autoleucel Injection in the treatment of Relapsed or Refractory acute lymphoblastic leukemia. The study consists of screening period including leukapheresis, treatment period, and follow-up period (2 years at most).

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
200
Inclusion Criteria
  1. Age ≥ 18 years;
  2. Diagnosed with relapsed or refractory B-cell acute lymphoblastic leukemia;
  3. Patients deemed eligible for receiving commercial Inaticabtagene Autoleucel injection treatment as determined by the investigator;
  4. Patients voluntarily participate in this study and sign an informed consent form. For patients lacking full legal capacity, informed consent must be obtained from their legal guardian
Exclusion Criteria

None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
overall survival2 years

OS is defined as the time from the start date of Inaticabtagene Autoleucel Injection infusion to the date of death due to any cause.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (10)

Peking University People's Hospital

🇨🇳

Beijing, Beijing, China

Peking University Third Hospital

🇨🇳

Beijing, Beijing, China

Zhujiang Hospital of Southern Medical University

🇨🇳

Guangzhou, Guangdong, China

Henan Cancer Hospital Affiliated Cancer Hospital of Zhengzhou University

🇨🇳

Zhengzhou, Henan, China

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

🇨🇳

Wuhan, Hubei, China

The Affiliated Hospital of Xuzhou Medical University

🇨🇳

Xuzhou, Jiangsu, China

Qilu Hospital of Shandong university

🇨🇳

Jinan, Shandong, China

Tongji Hospital of Tongji University

🇨🇳

Shanghai, Shanghai, China

West China School of Medicine/West China Hospital of Sichuan University

🇨🇳

Chengdu, Sichuan, China

Institute of Hematology & Blood Diseases Hospital

🇨🇳

Tianjin, Tianjin, China

© Copyright 2025. All Rights Reserved by MedPath